Whenever possible, use seamless tub and shower units to eliminate seams and reduce reliance on sealants. Where two-, three-, or four-piece units are necessary, (a bath remodel, for instance), use manufacturer-recommended sealing methods.
Tile is a frequent choice around tubs and showers. Unfortunately, this is not the preferred material from a durability standpoint: grout can crack and leak, it is difficult to clean, and it may contribute to mold growth. If tile is used, be sure to use a cementitious, glass-mat, or fiber-reinforced backer board meeting 2012 IRC R702.4.2 behind it—never paper-faced drywall or “greenboard.” Additional membrane products for walls and joints, along with gaskets to go around piping, are available and may be considered.